Are Clean, Healthy Arteries the Next Big Thing in Cardiovascular Health

Are Clean, Healthy Arteries the Next Big Thing in Cardiovascular Health

Cardiovascular Health

The isolation of chitin-glucan molecules obtained from the fungus Aspergillus Niger has led to several important breakthrough studies creating quite a buzz in the nutraceutical market. Making its debut several years ago in the beauty market, chitin-glucan has been successfully launched as a skin rejuvenating and hydration agent in cosmetics. More recently thanks to the collaborative research efforts of the Universities of Liege (Belgium), Louvain (Belgium) and Montpellier (France) chitin-glucan has been introduced to us as a novel approach to supporting clean, healthy arteries and promoting cardiovascular health.

Artinia is the registered trademark name for chitan-glucan developed by Stratum Nutrition, a Missouri-based company. Derived from natural, non-GMO sources Stratum Nutrition has already gained self-affirmed Generally Recognized as Safe (GRAS) status for Artinia and has begun an educational campaign for its awareness as a fiber heart health and weight management ingredient. 1 Flanked by substantial research studies, consumers can expect Artinia to hit the heart health market as early as next year.

Artinia – a Novel Approach to Supporting Cardiovascular Health

Scientists believe that Artinia prevents artery blockage by managing oxidative stress and protecting the system from the damaging effects of modern lifestyles and unhealthy diets. The research team at the Hospital Center of the University of Liege, Department of Diabetology, Nutrition and Metabolic Diseases conducted a 4-week preclinical human study. The control group, consisting of 30 slightly overweight volunteers, was given a dose of 1.5 grams of Artinia, three times a day without any change in dietary habits. 2

The results showed a decrease in blood triglyceride levels and about a 26 percent reduction in the concentration of oxidized-LDL. Researchers believe a combination of pathways stimulated greater lipid catabolism resulting in lower volumes of circulating lipids and a 20 percent reduction in triglyceride concentration when compared to the placebo group. The study showed that the implications of Artinia on cardiovascular health are enormous. A reduced level of oxidized-LDL in the blood results in lower inflammatory reaction in the arteries, thereby limiting the formation of plaque.

Meeting Cardiovascular Health Needs with Artinia

As a heart healthy fiber that keeps arteries clean by limiting plaque formation, Artinia has taken supplement manufacturing of heart health supplements to the next level. Cardiovascular health is already a top priority for consumers but there are more reasons than that to seriously consider introducing this novel ingredient in your product line.

Cardiovascular diseases (CVDs) include high blood pressure, atherosclerotic coronary heart disease, heart failure, stroke, and congenital cardiovascular defects. Artinia spells good news for the nearly 83 million Americans who suffer from one or more types of cardiovascular disease, according to statistics from the Centers of Disease Control and Prevention. 3 A few more statistics on CVDs will help readers understand the gravity of this problem:

  • CVDs are the leading cause of death around the world. The World Health Organization estimates that 24 million will die from cardiovascular disease between 2009 and 2030, largely because of the increased incidences of type 2 diabetes, obesity and other lifestyle-related health concerns. 4
  • According to the National Institute of Aging, around 40 percent of all deaths in the United States are related to cardiovascular disease and about 80 percent of those who die from cardiovascular disease occur in the same age group – 65 years and older. 5
  • According to the Center for Disease Control and Prevention, for women aged 25-44 years heart disease is the third leading cause of death; for women aged 45-64 years it is the second leading cause of death. 6

Heart Healthy Ingredients – a Fast Growing Market

Frost & Sullivan valued revenues for the United States heart health ingredients market at $563 million in 2008 and projects a fast growth for this market. It is projected to exceed $1 billion by 2012, and $2 billion by 2015. The projected CAGR exceeds 20 percent (2008-2015). New product launches in the heart or cardiovascular health segment have nearly tripled in the past 5 years and now account for 1.5 percent of the total food and beverage launches. 7

Heart supplements revenue in the combined Natural and Food, Drug and Mass Market Channels exceed $1 billion. While the current market targets products that are formulated to reduce LDL cholesterol, blood pressure, inflammation or oxidative stress, and lower triglycerides, the most popular segment is products that help reduce cholesterol. 8

According to a 2008 Natural Marketing Institute Health & Wellness Trends Survey, about 75 percent of the general population said they used heart-healthy foods/beverages in the past year. More than half of these indicate heart-healthy benefits prompt them to buy certain foods/beverages. About 19 percent of consumers reported using heart health supplements. 9

Applications for Artinia

Artinia contains chitan-glucan which is the main component in the cell walls of the fungus, Aspergillus Niger. Derived from a fermentation process, the free-flowing, odorless powder is yellow-brown and can be used in products such as muffins, cereals, breads, cookies, nutrition bars and meal replacements. With the exception of clear beverages, Artinia can be used as a heart-healthy ingredient in the manufacturing of smoothies, drinkable yogurts, fruit juices, energy and sports drinks. New products launches in the dietary supplement industry are expected to be in the market by next year.

Manufacturing Cardiovascular Health Supplements

One way to start selling well-formulated supplements for heart health is by contacting an experienced supplement manufacturer. Nutricap Labs provides customizable contract manufacturing solutions that optimize high-quality products, cost-efficiency and speed of delivery. Call (800) 494-6154 to speak to one of our Production Specialists or submit your request to receive a free quote from us in 48 hours or less. Help your customers take care of their cardiovascular health by developing a diverse range of heart healthy products.


1. Artinia for Heart Health Gets GRAS Approval, Nutritional Outlook, February 9, 2011.

2. Chitin-Glucan: A Revolution from Inside, Nutraceutical Business & Technology, Volume 4 Number 6 November/December 2008, pg 22.

3. Heart Disease and Stroke Prevention, Addressing the Nation’s Leading Killers: At a Glance 2011, Centers for Disease Control and Prevention,

4. World Health Organization, Fact Sheet 137, 2009

5. Age-associated cardiovascular changes in health: impact on cardiovascular disease in older persons, Heart Fail Rev. 2002 Jan;7(1):29-49. PMID: 11790921.

6. February is American Heart Month, Centers for Diseases Control and Prevention,

7. Frost & Sullivan; NBJ Report 2008.

8. Innova Database, 12-month period ending 4-2010 (Source: Supply Side Emerging Market Opportunities in Cardiovascular Health, May 2011.

9. Natural Marketing Institute’s 2008 Health & Wellness Trends Database (HWTD). (Source: Supply Side Emerging Market Opportunities in Cardiovascular Health, May 2011.

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