Natural Approaches to Lowering Cholesterol

Lowering Cholesterol SupplementsCholesterol is a soft, waxy-like substance found in the bloodstream. It is an essential component of cell membranes and promotes healthy cell functions. However, since cholesterol and other fats do not dissolve in the blood, they therefore have to be transported to and from cells by special carriers called lipoproteins. In the case of cholesterol these carriers are called low density lipoproteins (LDL) and high density lipoproteins (HDL).

  • The major cholesterol carrier is LDL, also known as the "bad" cholesterol. If there is too much of LDL in the body, it accumulates in the arterial walls that feed the heart and brain leading to the formation of plaque inside the arteries. This may lead to clogged arteries and heart disease.
  • HDL transports about one-fourth to one-third of the cholesterol. HDL is the "good" cholesterol and is believed to slow the growth of plaque formation by removing it from the body.

With heart disease being the number one cause of death in the United States, most people today understand the need to maintain high HDL and low LDL levels to promote heart health. 1

For some people, possessing low LDL counts is inherited. But for many others, diets and lifestyle play a major role. Other factors that may lead to the accumulation of unhealthy cholesterol include excess weight, lack of exercise, smoking, excess alcohol consumption and mental stress. Aging is also known to increase cholesterol levels in both men and women. After menopause, women are particularly prone to heart disease because estrogen hormones are believed to have a protective influence on the heart. The loss of estrogen is said to play a role in increasing the risk of heart disease in women after menopause. 2

Cholesterol is measured by a blood test called a lipoprotein profile. This profile provides information on the total cholesterol level, HDL and LDL counts as well as triglyceride (blood fats) count in the blood. While the total cholesterol count is important and should be less than 200 mg/dl, it is the HDL and LDL counts that are vital. More than 60 mg/dL of HDL is considered as low risk for heart disease, while an LDL count between 100 to 129 mg/dL, along with a triglyceride count of less than 150 mg/dL, is considered optimal for supporting heart health.

Several natural remedies exist for those who suffer from fluctuating cholesterol levels. Many of these have been well-researched and indicate safety and efficacy. Formulators have a wide range of scientifically supported ingredients they can choose from to meet the needs of people looking to lower their cholesterol.

The following are examples of some ingredients that are believed to help lower cholesterol.

Phytosterols, or plant sterols, which are similar in structure to cholesterol, compete for absorption in the digestive tract. This may be the mechanism by which phytosterols help to lower plasma cholesterol levels. 3 A more recent study shows that consumption of plant sterols (up to 9 grams) may reduce serum LDL cholesterol concentrations up to 17.4 percent. 4 In 2003, the FDA allowed "dietary supplements to bear the heart health claim in labeling when formulated with 0.65 grams of phytosterol esters or 0.4 grams free phytosterols per serving."

Tocotrienols are part of the Vitamin E family. Pilot studies show that unlike statins, which lower CoQ10 levels in the body, tocontrienols may help to increase CoQ10 levels in the body by up to 20 percent, while decreasing total cholesterol by 13 percent and LDL by 15 percent. 5 CoQ10 is a vitamin-like substance needed by the body to support several functions and maintain energy levels. Tocotrienols may be combined with polymethoxylated flavones (PMFs) derived from citrus fruit peels to enhance the effects of supplements that help to lower cholesterol.

Along with Vitamin E, Vitamin B3 (or niacin) is also known to increase HDL cholesterol and decrease overall cholesterol. 6 Vitamins such as tocotrienol and niacin, as part of a daily multi-vitamin regimen, are considered to be effective nutrients for supplements that support the reduction of cholesterol.

Policosanol, a combination of long-chain fatty alcohols derived from the wax of sugarcane, honeybee or rice bran was shown to be effective in reducing cholesterol levels. A study published in the American Heart Journal(2002) lowered total cholesterol by 17 percent; LDL by 21 percent; and increased HDL by 8 percent. 7

Soy proteins also show cholesterol-lowering benefits along with beta glucans found in mushrooms, yeast, oats and barley. In 1997, the FDA approved a health claim for foods or supplements containing at least 3 grams of oat bran can be marketed as "lowering cholesterol" supplements.

Fish oil - An EPA liquid study done in Japan (JELIS) found that in a group of 18,000 participants between 1996 and 1999, fish oils that are abundant in EPA and DHA are as effective as statin drugs in reducing unhealthy cholesterol levels. Though research is inconclusive, the FDA allows supplement manufacturers to make supportive claims stating that the consumption of EPA and DHA omega-3 fatty acids may reduce the risk of Coronary Heart Disease CHD. Daily intakes of up to 3 grams of marine-sourced omega 3 fatty acids are considered to be GRAS (generally recognized as safe). Krill oil, a marine source of omega-3 fatty acids derived from Krill, is another popular ingredient used to lower cholesterol in supplements. 8-9 Plant sources of omega-3s such as flaxseeds also have cholesterol-lowering effects. Flaxseed supplementation was seen to decrease both serum total cholesterol and LDL by 6 percent. 10

More natural cholesterol supplements include pure, defatted cocoa. This type of cocoa is rich in antioxidants and, may help to lower cholesterol and LDL levels by 6 mg/dL, according to a study conducted in China. 11

The digestive system is mainly responsible for the maintenance of cholesterol levels in the body. Dietary enzymes, such as protease along with whey protein, are considered to play a modifying role in reducing LDL and increasing HDL counts. Although studies that quantify the effect dietary enzymes have on cholesterol levels are not available, dietary enzymes are considered to be an effective ingredient in supplements to help reduce cholesterol.

Our team of highly qualified product advisors have a firm understanding on the latest research developments and what consumers are looking for to reduce cholesterol. Request your free quote today and let the experts at Nutricap Labs custom design the best "lowering cholesterol" supplements for your product line.

References:

1. Heart Attack and Angina Statistics, American Heart Association: http://www.americanheart.org/presenter.jhtml?identifier=4591

2. The epidemiology of coronary heart disease and estrogen replacement in postmenopausal women, Prog Cardiovasc Dis. 1995 Nov-Dec;38(3):199-210.

3. Heinemann T, Axtmann G, von Bergmann K. "Comparison of intestinal absorption of cholesterol with different plant sterols in man. "Eur J Clin Invest. 1993 Dec;23(12):827-31.

4. Mensink RP, et al. "Plant stanols dose-dependently decrease LDL-cholesterol concentrations, but not cholesterol-standardized fat-soluble antioxidant concentrations, at intakes up to 9 g/d." Am J Clin Nutr. 2010 Jul;92(1):24-33.

5. Am. J. Clin. Nutr ., Vol. 53, pp. 1021S-1026S

6. Ceska R, et al. "[Hyperlipoproteinaemia and dyslipoproteinaemia II. Therapy: non-pharmacological and pharmacological approaches]. [Article in Czech]" Vnitr Lek. 2010 Jul;56(7):647-54.

7. Gouni-Berthold I, Berthold HK. "Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent." Am Heart J. 2002 Feb;143(2):356-65.

8. Yokoyama M., et al. "Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis." Lancet. 2007 Mar 31;369(9567):1090-8.

9. Ulven SM, et al. "Metabolic Effects of Krill Oil are Essentially Similar to Those of Fish Oil but at Lower Dose of EPA and DHA, in Healthy Volunteers." Lipids. 2010 Nov 2.

10. Lucas EA et al. Flaxseed improves lipid profile without altering biomarkers of bone metabolism in post-menopausal women. J Clin Endocrinol Metab 2002; 87:1527

11. Jia L., et al "Short-term effect of cocoa product consumption on lipid profile: a meta-analysis of randomized controlled trials." Am J Clin Nutr. 2010 Jul;92(1):218-25.

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2009 & 2010 Inc. 500 Award
 
In 2009 and 2010, Nutricap Labs was named to Inc. Magazine's list of the 5,000 fastest-growing, privately held companies in America. This annual list ranks the 5,000 fastest-growing companies according to revenue and percentage growth. In 2009, Nutricap Labs was named the 42nd fastest-growing company in America and in 2010 was named the 413th fastest-growing company in America.

 

Ernst & Young Entrepreneur of the Year

 

In June of 2010, Nutricap Labs Executive Vice President of Sales and Operations, Jason Provenzano, was named a finalist for Ernst & Young's Entrepreneur of the Year Award. Founded in 1986, this year-long program is the only global business recognitions program held on 6 continents, in more than 50 countries and over 135 cities. Entrepreneur of the Year honors entrepreneurs whose vision, courage, and achievements have sustained successful growing business ventures.

 

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- Gerry David


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Bakersfield, CA


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- Jackie H.
Mahwah, NJ


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Brooklyn, NY


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- Nick C.
Pittsburgh, PA

"When it came to supplement manufacturer my choice was easy. Nutricap labs made all of my dreams come true. They provided me with the best possible service a supplement manufacturer could provide. They are always available for me to contact and I feel very close to them. I had tried some other supplement manufacturer companies in the past but never could get a straight answer. Nutricap labs are defiantly leaders in their industry."

- Nick C.
Online Marketer
Pittsburgh, PA


Quality Guarantee Testimonial

- Tom V.
Little Neck, NY

"I really didn't know what to do, which is normal for me. I find it hard in making decisions when problems come up. Since dealing with Nutricap labs I have been able to put my head on my pillow at night. Their quality guarantee is the best around. I had an incident where my labels were not adhering to the bottle when I received my order. No fault of theirs, they took the product back and redid it to satisfy me. They really have some customer service staff over there."

- Tom V.
Little Neck, NY


Testimonial

- Jon K.

"Nutricap Labs has and continues to provide us with the highest level of quality and timely manufacturing that we have ever experienced. Nowhere else can you find a company that can produce, warehouse, and ship your products for you than with Nutricap."

- Jon K.


GMP Certified Manufacturer Testimonial

- Gerry David

"We are a 20 year old company that distributes its own brand of 60 dietary supplements through several thousand independent health food stores and thousands of independent pharmacies. We searched for several months for a new herbal manufacturer that would meet our high quality standards and delivery expectations on a consistent basis. Nutricap Labs, an herbal dietary supplement manufacturer, met all of the criteria we set. Certified GMP, FDA registered drug facility and exceptionally good lead times, all with one herbal dietary supplement manufacturer. We truly feel Nutricap Labs is the premier herbal manufacturer in the country."

- Gerry David


Gel Manufacturer Testimonial

- Steve L.

"Nutricap did a tremendous job helping me get my bodybuilding supplement line off the ground. So when the time came to find a company to manufacture my line of gel products, the only choice for me was Nutricap Labs. Your quick turnaround time and attention to detail helped me launch my products weeks before I had anticipated."

- Steve L.


Organic Manufacturer Testimonial

- Shelley W.

"When we first came to Nutricap Labs, we were a new company that was looking to develop our own line of organic products. From beginning to end, Nutricap Labs provided superior service as our organic manufacturer. From first contact to finished product, they were helpful in guiding us through the manufacturing process and producing a superior product. It has been 5 years now since our initial organic product line was launched and we would not consider using any other manufacturer except Nutricap Labs."

- Shelley W.


Nutrition Manufacturer Testimonial

- Pam C.

"I searched high and low for a nutritional supplement manufacturer that could meet my product needs. I then came across Nutricap Labs and have not used another manufacturer since. I found their staff to be both personable and professional and they were willing to take the time to speak to me about my product needs. Anyone that is considering starting a product line should contract Nutricap Labs."

- Pam C.


Sports Nutrition Manufacturer Testimonial

- Marc G.

"I had been using a local manufacturer for my sports nutrition manufacturing needs. However, they never offered me 100% of the services I was looking for. Namely drop shipping and order fulfillment. I then came across an advertisement for Nutricap Labs in a trade magazine. Since working with Nutricap Labs, I have developed two successful product lines and use them for all of my drop shipping and order fulfillment needs. We're in the process of developing our third product line with Nutricap and we're excited to see what they can come up with this time around!"

- Marc G.


Contract Manufacturing Testimonial

- J. Smith

"We have been in business for over 30 years and have seen and worked with many manufacturers. Nutricap Labs has out-performed all others in quality, cost and delivery time. You will not find a contract manufacturer more capable of handling every aspect of a project from inception to delivery. We highly recommend Nutricap Labs and are looking forward to the launch of many successful products with them."

- J. Smith


Contract Manufacturing Testimonial

- J. Shell

"Nutricap Labs exceeds any other manufacturer I've ever dealt with in the past. They were able to duplicate our existing product line and they were able to help our company expand by working with us to create several new products. Nutricap Labs has been able to accomplish all this with better customer service than I have ever received and turn around times that allow us to maintain inventory effectively. They truly are full service and they take all the headaches out of ordering product."

J. Shell


Contract Manufacturing Testimonial

— Rebecca C. Victoria, TX

As an owner of a health club, many of my customers told me that they had spent hundreds of dollars on Acai products that just didn't seem to work for them. It was shortly thereafter that I decided to manufacture my own Acai product. The sales advisors at Nutricap Labs assured me that their unique freeze-drying technology would guarantee me a first-rate Acai product. Well, they were absolutely correct! I began selling my product in my store a few months ago and my customers began noticing results almost immediately. I absolutely recommend Nutricap Labs to anyone looking for a quality Acai manufacturer.

— Rebecca C.
Victoria, TX


Order Fulfillment Testimonial

- C. Davis

"We've dealt with a variety of fulfillment service companies over the past two years and have had mixed results. Since dealing with Nutricap Labs, however, our general operations have been running smoothly. Their hands on approach to customer service and their attention to detail is something that was immediately noticeable when we began with their services. Due to their professional handling of all our shipping and fulfillment services, we are able to focus on our core competencies and our customers. In addition, we've seen an increase in sales volume over 250% in the past quarter alone."

- C. Davis


Order Fulfillment Testimonial

— Rick A. Greensboro, NC

For years, I had handled my company's order fulfillment services. But when my business started to take off, I knew that I needed to devote more time to expanding my business and less time fulfilling orders. Since Nutricap Labs was already handling the manufacturing of my product, I asked them to begin fulfilling my orders as well. I have made many decisions during my professional career and I can say without hesitation that this change was definitely one of the smartest business moves I have ever made.

— Rick A.
Greensboro, NC


Order Fulfillment Testimonial

— Carlos T. Scarborough, ME

I have worked with several fulfillment companies over the years and for some reason, we always had issues getting the results we desired. At times, it felt like I was spending more time helping them than they were helping me! I then turned to Nutricap Labs to handle our manufacturing, packaging and fulfillment needs. Almost immediately after hiring Nutricap, I noticed a vast improvement in the operations of my company... and even the quality of my product! I can definitely understand why Nutricap prides itself on being the premier full service nutraceutical company in the industry.

— Carlos T.
Scarborough, ME


Softgel Manufacturer Testimonial

— Beth F.
Joliet, IL

I was looking for a softgel manufacturer that could not only create a quality product for me, but could get it produced in the shortest amount of time possible. Nutricap Labs' ability to produce a quote for me in 24 hours literally shaved weeks off of the entire manufacturing process. While I am convinced that it would have taken any other softgel manufacturer months to get this project completed, Nutricap was able to get it done in roughly 3 weeks. By the following week, I was able to begin selling my product.

— Beth F.
Joliet, IL


All Natural Vitamins & Supplements Testimonial

— Kelly and Sean Loveland, OH

Because our product line caters to health-conscious consumers, we had to make sure that the manufacturer we selected used only the finest all natural ingredients. Failing to do this would surely spell doom for our company before we even got out of the gate. Our Nutricap Labs product advisor explained the criteria for how ingredients are selected for all natural vitamins and supplements and how our product would be manufactured. We feel completely at ease knowing that our manufacturing needs are in the very capable hands of Nutricap Labs.

— Kelly and Sean
Loveland, OH


Vegan Manufacturer Testimonial

— M. Furman Marietta, GA

As a company whose product must meet certain dietary guidelines, it was important that the contract manufacturer that we selected took all the necessary precautions in creating our product. Nutricap Labs assured us that they used a separate production unit that was used specifically for products such as ours. The flexibility that Nutricap Labs offers customers such as me truly is first-rate.

— M. Furman
Marietta, GA


Kosher Manufacturer Testimonial

— M. Furman Marietta, GA

As a company whose product must meet certain dietary guidelines, it was important that the contract manufacturer that we selected took all the necessary precautions in creating our product. Nutricap Labs assured us that they used a separate production unit that was used specifically for products such as ours. The flexibility that Nutricap Labs offers customers such as me truly is first-rate.

— M. Furman
Marietta, GA


Non Allergenic Vitamin Manufacturer Testimonial

— M. Furman Marietta, GA

As a company whose product must meet certain dietary guidelines, it was important that the contract manufacturer that we selected took all the necessary precautions in creating our product. Nutricap Labs assured us that they used a separate production unit that was used specifically for products such as ours. The flexibility that Nutricap Labs offers customers such as me truly is first-rate.

— M. Furman
Marietta, GA


Gluten Free Vitamins & Supplements Testimonial

— M. Furman Marietta, GA

As a company whose product must meet certain dietary guidelines, it was important that the contract manufacturer that we selected took all the necessary precautions in creating our product. Nutricap Labs assured us that they used a separate production unit that was used specifically for products such as ours. The flexibility that Nutricap Labs offers customers such as me truly is first-rate.

— M. Furman
Marietta, GA


Vitamins Jars Testimonial

— Timothy D. Sedona, AZ

Being that I've been in the nutraceutical industry for more than 25 years, my experience has taught me one of the most overlooked elements in creating a product line is the packaging that is used. While you may have the greatest product ever to hit the industry, it means nothing if your product doesn't arrive at its final destination in the same condition that it left the factory and if your customers don't like the way it looks and feels in their hands. For these reasons, I 100% rely on Nutricap Labs' packaging solutions. I have used a number of their packaging options (jars, blister packs, bottles and cartons) in the past and all of my products arrive safely every time. More importantly, my customers know that my products will stay fresh and will be easy to access as long as I'm using packaging solutions from Nutricap Labs.

— Timothy D.
Sedona, AZ


Vitamin Bottles Testimonial

— Timothy D. Sedona, AZ

Being that I've been in the nutraceutical industry for more than 25 years, my experience has taught me one of the most overlooked elements in creating a product line is the packaging that is used. While you may have the greatest product ever to hit the industry, it means nothing if your product doesn't arrive at its final destination in the same condition that it left the factory and if your customers don't like the way it looks and feels in their hands. For these reasons, I 100% rely on Nutricap Labs' packaging solutions. I have used a number of their packaging options (jars, blister packs, bottles and cartons) in the past and all of my products arrive safely every time. More importantly, my customers know that my products will stay fresh and will be easy to access as long as I'm using packaging solutions from Nutricap Labs.

— Timothy D.
Sedona, AZ


Vitamin Cartons Testimonial

— Timothy D. Sedona, AZ

Being that I've been in the nutraceutical industry for more than 25 years, my experience has taught me one of the most overlooked elements in creating a product line is the packaging that is used. While you may have the greatest product ever to hit the industry, it means nothing if your product doesn't arrive at its final destination in the same condition that it left the factory and if your customers don't like the way it looks and feels in their hands. For these reasons, I 100% rely on Nutricap Labs' packaging solutions. I have used a number of their packaging options (jars, blister packs, bottles and cartons) in the past and all of my products arrive safely every time. More importantly, my customers know that my products will stay fresh and will be easy to access as long as I'm using packaging solutions from Nutricap Labs.

— Timothy D.
Sedona, AZ


HDPE Packaging Testimonial

- David Y.
New York, NY

"Nutricap far exceeded my expectations with my packaging needs. They were able to develop the packaging I envisioned and produce my product in record time. Although there were many options to choose from which was a bit overwhelming, Nutricap Labs assisted me in making the perfect packaging choice for my product. The turnaround time for this project was a shock and I was ready to launch my product a month earlier than scheduled!"

- David Y.
New York, NY


Pet Bottles Testimonial

- David Y.
New York, NY

"Nutricap far exceeded my expectations with my packaging needs. They were able to develop the packaging I envisioned and produce my product in record time. Although there were many options to choose from which was a bit overwhelming, Nutricap Labs assisted me in making the perfect packaging choice for my product. The turnaround time for this project was a shock and I was ready to launch my product a month earlier than scheduled!"

- David Y.
New York, NY


BOPP Packaging Testimonial

- David Y.
New York, NY

"Nutricap far exceeded my expectations with my packaging needs. They were able to develop the packaging I envisioned and produce my product in record time. Although there were many options to choose from which was a bit overwhelming, Nutricap Labs assisted me in making the perfect packaging choice for my product. The turnaround time for this project was a shock and I was ready to launch my product a month earlier than scheduled!"

- David Y.
New York, NY


Storage Capabilities Testimonial

— M. Detrone Monroe, NY

"One of the prerequisites I had when I was selecting a new vitamin manufacturer was whether or not they had a warehouse facility so I could store my products on-site. Although I found several manufacturers that had storage capabilities, Nutricap Labs stood out from the rest because of their ability to not only store my products, but they could also handle my drop shipping and order fulfillment needs. This enabled me to devote more time to growing my business and maximize my revenue."

— M. Detrone
Monroe, NY